Statistical analysisWe based sample size estimates on the mean

We extracted data on moderate exacerbations over the complete trial period from electronic medical records at 24 months. We defined a moderate exacerbation as a worsening of daily symptoms that led a patient’s physician to prescribe systemic corticosteroids, antibiotics, or both, without hospital admission. A severe exacerbation occurred when worsening symptoms required a hospital admission.Statistical […]

As compliance with end of life wishes was the primary end

We hypothesised that coordinated advance care planning would improve end of life care, the perceptions of the quality of care, and levels of stress, anxiety, and depression in surviving relatives. We report the results of a single blinded randomised controlled trial examining the impact of advance care planning on these outcomes in elderly medical […]